Reaxys Commercial Substances Database (RCS DB) is a new feature of the Elsevier Reaxys platform that provides detailed information on commercially available chemical substances and suppliers. The expanded solution enables users to better search, find, filter commercially available compounds and their suppliers, which will better support the substance ordering process via Reaxys. Information about commercially available compounds constitute an integral part of Reaxys, allowing seamless integration and usage of data in various user workflows including synthesis planning and retrosynthesis. For more information about Reaxys, visit https://www.elsevier.com/solutions/reaxys.